The management of locally advanced pancreatic cancer (LAPC) patients remains controversial. Better discrimination for the prediction of overall survival (OS) at baseline is needed to improve therapeutic decisions and optimize clinical trials design. We proposed a prognostic score and a nomogram to address this issue.
Prediction tools are designed to help physicians to predict patient’s risk profile and individual prognosis that may help to guide clinical management. They may also be used by researchers to optimize the design of future clinical trials and thus to ensure well-balanced arms for risk profile.
If you are a patient, we recommend that you use these tools only in consultation with your healthcare provider.
About Dewi VERNEREY
Dewi Vernerey is a research engineer in epidemiology and biostatistics who received a master’s degree cum laude from Joseph Fourier University (Grenoble, France) with a major in engineering statistics. He defended a PhD in epidemiology and statistics in 2016. His PhD research focused on statistical methodology for risk prediction and prognostic score construction in oncology and kidney transplantation.
About Sophie PAGET-BAILLY
Sophie Paget-Bailly is a research engineer in epidemiology and clinical research. She passed with honours the East of France inter-region master’s degree in public health and occupational and environmental risks. During the master’s degree’s internship in the Interregional Epidemiology Unit of Bourgogne/Franche-Comté, she realized a quantitative health risk assessment in the context of chemical contamination of groundwater. She defended a PhD in Public Health and Epidemiology in Paris XI University, Doctoral School 420, working in the Centre for Research in Epidemiology and Population Health in Villejuif, France. Her PhD research focused on occupational exposures and head and neck cancer.
About Franck BONNETAIN
Franck Bonnetain is a full Professor in epidemiology and biostatistics who received a master’s degree in clinical epidemiology from School of Public Health (Nancy, France). He obtained a PhD in public health with epidemiology and statistics specialties in 2005 as well asthe “Habilitation à diriger des recherches” (Professoral capability) in 2010.